Comparison Between the Polymyxins and Gentamicin in Preventing Endotoxin-Induced Intravascular Coagulation and Leukopenia
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چکیده
منابع مشابه
Comparison between the polymyxins and gentamicin in preventing endotoxin-induced intravascular coagulation and leukopenia.
Three antimicrobial agents were evaluated as to their ability to neutralize the toxic effects of endotoxin in rabbits. These consisted of two cyclic polypeptides, polymyxin B sulfate and colymycin M (sodium colistimethate), and an aminoglycoside, gentamicin sulfate. Polymyxin B regularly prevented endotoxin-induced leukopenia, thrombocytopenia, and disseminated intravascular coagulation. Colymy...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1971
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.4.5.563-566.1971